The C&O Canal 100-mile race is held along the picturesque C&O Canal, beginning and concluding at Camp Manidokan near Knoxville, Maryland. This largely flat course presents a unique chance for both novice and seasoned ultrarunners to achieve their personal bests while soaking in the beauty of the surroundings. Participants can expect a race that balances challenge with the appeal of a stunning route, making it a welcoming environment for anyone ready to tackle the 100-mile distance.